 | Doctor Strange 2 (2020) as Stephen Strange / Doctor Strange |
 | Mowgli (2019) as Shere Khan |
 | Untitled Avengers Movie (2019) as Stephen Strange / Doctor Strange |
 | The Grinch (2018) as Grinch |
 | Avengers: Infinity War (2018) as Dr. Stephen Strange |
 | Mark Gatiss: A Study in Sherlock (2018) as Himself |
 | The Current War (2018) as Thomas Edison |
 | Thor: Ragnarok (2017) as Stephen Strange / Doctor Strange |
 | The Child in Time (2017) as Stephen Lewis |
 | Walk with Me (2017) as Narrator |
 | Sherlock: The Final Problem (2017) as Sherlock Holmes |
 | The Lying Detective (2017) as Sherlock Holmes |
 | The Six Thatchers (2017) as Sherlock Holmes |
 | Naples '44 (2016) as Norman Lewis |
 | Doctor Strange (2016) as Stephen Strange / Doctor Strange |
 | Shakespeare Live! From the RSC (2016) |
 | Zoolander 2 (2016) as All |
 | Sherlock: The Abominable Bride (2016) as Sherlock Holmes |
 | National Theatre Live: Hamlet (2015) as Hamlet |
 | Black Mass (2015) as Billy Bulger |
 | The Battle of Dol Guldur (2015) as Necromancer (voice) |
 | Lennon or McCartney (2014) as Himself (archive footage) |
 | 9 Kisses (2014) as Man at Costume Party |
 | The Hobbit: The Battle of the Five Armies (2014) as Smaug / Necromancer (voice) |
 | Penguins of Madagascar (2014) as Classified (voice) |
 | The Imitation Game (2014) as Alan Turing |
 | The Empty Hearse (2014) as Sherlock Holmes |
 | Unlocking Sherlock (2014) as Himself / Sherlock Holmes |
 | His Last Vow (2014) as Sherlock Holmes |
 | The Sign of Three (2014) as Sherlock Holmes |
 | August: Osage County (2013) as Little Charles Aiken |
 | Wholock (2013) as Sherlock Holmes |
 | The Hobbit: The Desolation of Smaug (2013) as Smaug / The Necromancer |
 | Jerusalem (2013) as Narrator |
 | Little Favour (2013) as Wallace |
 | National Theatre Live: Fifty Years on Stage (2013) as Rosencrantz |
 | 12 Years a Slave (2013) as William Ford |
 | The Fifth Estate (2013) as Julian Assange |
 | Star Trek Into Darkness (2013) as Khan Noonien Singh |
 | Electric Cinema: How to Behave (2012) as Humphrey Bogart |
 | The Hobbit: An Unexpected Journey (2012) as Necromancer |
 | Parade's End (2012) as Christopher Tietjens |
 | The Reichenbach Fall (2012) as Sherlock Holmes |
 | The Hounds of Baskerville (2012) as Sherlock Holmes |
 | A Scandal in Belgravia (2012) as Sherlock Holmes |
 | War Horse (2011) as Maj. Jamie Stewart |
 | Wreckers (2011) as David |
 | Tinker Tailor Soldier Spy (2011) as Peter Guillam |
 | National Theatre Live: Frankenstein (2011) as The Creature / Victor Frankenstein |
 | The Great Game (2010) as Sherlock Holmes |
 | The Blind Banker (2010) as Sherlock Holmes |
 | The Whistleblower (2010) as Nick Kaufman |
 | A Study in Pink (2010) as Sherlock Holmes |
 | Third Star (2010) as James |
 | Four Lions (2010) as The Negotiator |
 | Van Gogh: Painted with Words (2010) as Vincent Van Gogh |
 | Burlesque Fairytales (2010) as Henry Clark |
 | Creation (2009) as Joseph Dalton Hooker |
 | The Turning Point (2009) as Guy Burgess |
 | Murder Is Easy (2009) as Luke Fitzwilliam |
 | The Other Boleyn Girl (2008) as William Carey |
 | Stuart: A Life Backwards (2007) as Alexander Masters |
 | Atonement (2007) as Paul Marshall |
 | Inseparable (2007) as Joe / Charlie |
 | Amazing Grace (2006) as William Pitt |
 | Starter for 10 (2006) as Patrick Watts |
 | Hawking (2004) as Stephen Hawking |
 | To Kill a King (2003) as Royalist |
 | Tipping the Velvet (2002) as Freddy |
| | Fields of Gold (2002) as Jeremy |
| | The War Magician as Jasper Maskelyne |
 | Brexit as Dominic Cummings |
| | Ironbark as Greville Wynne |
| | Flying Horse as Harry Larkyns |
 | Rogue Male |
| | How to stop time as Tom Hazard |
| | Let It Fall Back |
 | Gypsy Boy |
| | Magik as Lewis |
 | The Art of the Dab Catering Head Chef |
| | The Child in Time Executive Producer |
 | The Man Who Predicted 9-11 Vocal Coach |
| | How to stop time Producer |
| | Ironbark Executive Producer |
